提示：
1、投稿方式：在线投稿。
2、期刊网址：
https://www.journals.elsevier.com/bioorganic-and-medicinal-chemistry-letters
https://www.sciencedirect.com/journal/bioorganic-and-medicinal-chemistry-letters
3、投稿网址：https://www.editorialmanager.com/BMCL
4、期刊刊期：半月刊，每月1日、15日出版。
2021年10月23日星期六
投稿须知【官网信息】
Guide for Authors
Aims and scope
Bioorganic & Medicinal Chemistry Letters publishes research communications of outstanding significance and timeliness on topics at the interface of chemistry and biology, together with invited concise review articles. The journal publishes reports of experimental results in medicinal chemistry, chemical biology and drug discovery and design, emphasizing new and emerging advances and concepts in these fields. The aim of the journal is to promote a better understanding at the molecular level of life processes, and living organisms, as well as the interaction of these with chemical agents. The journal continues to be a major forum for the first publication of new chemical entities prior to them entering clinical trials.
The Journal welcomes papers on:
the medicinal chemistry and associated biology (including target identification and validation) of established or new disease targets
the reporting of the discovery, design or optimization of potent new compounds or biological agents
the analysis and discussion of structure-activity relationships and pharmacological issues relevant to drug design and action using in vitro and in vivo models, including the use of computational techniques when closely linked to experimental data
the reporting of "first-in-class" new therapeutic compounds
the chemical biology or bioorganic/bioinorganic chemistry that significantly advances knowledge of a biological mechanism
methodological advances that are chemistry-based and which significantly impact on medicine or biology
the preparation and examination of biotherapeutics for the treatment of pathophysiological disease states
the development of materials for specific therapeutic targeting
Manuscripts on phytochemistry, theoretical molecular dynamics and exclusively computational papers are out of scope. All manuscripts will be rigorously peer-reviewed by independent experts following an initial assessment by the Editors. Please note that BMCL is not suitable for straightforward reports of incremental advances. Above all the presentation of a rational basis and a sound underlying hypothesis for the work is of particular importance, whatever its exact field.
Bioorganic & Medicinal Chemistry Letters publishes research results of outstanding significance and timeliness in the fields of medicinal chemistry, chemical biology, bioorganic chemistry, bioinorganic chemistry, and related disciplines. Articles are in the form of communications reporting experimental or theoretical results of special interest. Hypothesis-driven theoretical studies containing complementary experimental reports are also welcome.
High-quality studies which are especially likely to meet these criteria, as compared to studies that simply report biological data for a series of newly-synthesised compounds. Examples include manuscripts
on the medicinal chemistry and associated biology of established or new disease targets, that report on potent new compounds and that analyse and discuss structure-activity relationships
on "first-in-class" new therapeutic compounds
on chemical biology, structural biology or bioorganic/bioinorganic chemistry that significantly advances knowledge of a biological mechanism
on novel methodological advances that are chemistry-based and which significantly impact on medicine or biology
Above all the presentation of a rational, hypothesis-driven basis for the work is of particular importance, whether its exact field.
The journal wishes to encourage rapid communications of important new data, especially on novel potential drugs. Full analytical data is therefore not required on all compounds described in the text, but it is now required on lead compounds. Authors are welcome to provide such data on all reported compounds, should they so wish: this should be placed in a Supplementary Data section and made available to reviewers.
The journal will no longer accept routine studies on series of compounds that are straightforward extensions of existing knowledge. Phytochemical and purely computational studies are generally more appropriate for specialized journals.
BMCL is flexible and will consider Communications with a range of lengths, up to a maximum length of normally no more than 10 printed pages. Longer manuscripts or full papers may be more suited to the companion journal Bioorganic and Medicinal Chemistry.
Submission Checklist
You can use this list to carry out a final check of your submission before you send it to the journal for review. Please check the relevant section in this Guide for Authors for more details.
Ensure that the following items are present:
One author has been designated as the corresponding author with contact details:
• E-mail address
• Full postal address
Email addresses for all authors should be supplied. Submission of a manuscript to BMCL is taken to mean that all authors are aware of, and agree to the submission.
All necessary files have been uploaded:
Manuscript:
• Include keywords
• All figures (include relevant captions)
• All tables (including titles, description, footnotes)
• Ensure all figure and table citations in the text match the files provided
• Indicate clearly if color should be used for any figures in print
• Include full synthetic and analytical data for lead compound(s)
• Include accession numbers for deposited crystal structures
Graphical Abstracts / Highlights files (where applicable)
Supplemental files (where applicable)
Further considerations
• Manuscript has been 'spell checked' and 'grammar checked'
• All references mentioned in the Reference List are cited in the text, and vice versa
• Permission has been obtained for use of copyrighted material from other sources (including the Internet)
• A competing interests statement is provided, even if the authors have no competing interests to declare
• Journal policies detailed in this guide have been reviewed
• Referee suggestions and contact details provided, based on journal requirements. These suggestions may be used by the editors, at their discretion. Please do not name colleagues in your institution, or with whom you have a current or recent professional link.
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